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WaveNeuro One FSCV System

Part Number
AF01FSCV1

The WaveNeuro® Fast Scan Cyclic Voltammetry (FSCV) Potentiostat System is a unique electrochemical instrument you will not find from other traditional electrochemical suppliers. We are excited to bring high quality, regularly available, and uniquely designed neuroelectrochemical research products to you. Created by FSCV scientists for FSCV scientists, the WaveNeuro is well-designed, of high quality construction, and supported by a company with over 40 years of history serving electrochemical researchers. The WaveNeuro seeks to fill the gap that exists for commercial fast-scan cyclic voltammetry (FSCV) systems.

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The WaveNeuro® Fast Scan Cyclic Voltammetry (FSCV) Potentiostat System is a unique electrochemical instrument you will not find from other traditional electrochemical suppliers. We are excited to bring high quality, regularly available, and uniquely designed neuroelectrochemical research products to you. Created by FSCV scientists for FSCV scientists, the WaveNeuro is well-designed, of high quality construction, and supported by a company with over 40 years of history serving electrochemical researchers. The WaveNeuro seeks to fill the gap that exists for commercial fast-scan cyclic voltammetry (FSCV) systems.

The WaveNeuro® Fast Scan Cyclic Voltammetry (FSCV) Potentiostat System is a unique electrochemical instrument you will not find from other traditional electrochemical suppliers. We are excited to bring high quality, regularly available, and uniquely designed neuroelectrochemical research products to you. Designed by FSCV scientists for FSCV scientists, the WaveNeuro is well-designed, of high quality construction, and supported by a company dedicated to supporting the instrument, as well as you the researcher. The WaveNeuro seeks to fill the gap that exists for commercial fast-scan cyclic voltammetry (FSCV) systems.

The WaveNeuro is available in single channel (WaveNeuro One), dual channel (WaveNeuro Two), and quad multichannel (WaveNeuro Four) configurations!

The WaveNeuro Potentiostat was designed for the scientist (neuroscientist, psychologist, physician, chemist, biologist, etc.) who seeks to study the link between the brain chemistry of electroactive species (such as monoamines, catecholamines like dopamine and serotonin, oxygen, peroxide, etc.) and physiology (such as structure, function, disease, neural transmission, etc.) and behavior (such as addiction, impulsivity, decision-making, etc.). Microdialysis, still a technique used in the field, can provide high spatial resolution for detection of these chemical species but offers poor temporal resolution. FSCV, as a technique, provides both high spatial and high temporal resolution. Coupled with carbon fiber microelectrodes, FSCV provides a well-established platform for in-vivo and in-vitro experimentation.

Traditionally, the products and instrumentation required to perform FSCV have only been available through scientific connections with developing laboratories. As the technique has grown in popularity, due in part to its relative ease of use, the availability of instrumentation has not followed the same trend. We are excited to bring such FSCV instrumentation to the market, thereby providing the robust technical, service, and sales support you have come to expect in the field of research instrumentation.

The WaveNeuro seeks to fill the gap that exists for commercial FSCV systems by providing systems with many novel features, such as:

  • We strive to have items in stock and ready to ship! Who can wait 8 weeks or more when your research productivity is on the line?
  • A system that breaks from the past, with an overall updated design, including: a “breakout box” built into and included with the WaveNeuro, intuitive and clearly-labeled connectors, in a small dimensional footprint.
  • Built for flexibility – includes behavioral input mapping to digital and analog input/output connections.
  • Designed with Pine Research modular headstage cable design, preventing that “pile of unknown headstage/cables” that so many labs make over time.
  • 1, 2, or 4 Channel Configurations now available!
The WaveNeuro One FSCV System is available as part of a product bundle. A product bundle is a combination of products that are compatible and often sold together for convenience and confidence. Below is a list of product bundles that contain WaveNeuro One FSCV System.
Basic System Bundle (No Additional Products Included)
Image
Bundle Name
Bundle Part #
WaveNeuro One FSCV Potentiostat (Basic Bundle)
[NEC-WN-ONE-B]
Bundled with National Instruments Interface Board and Cables
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Bundle Name
Bundle Part #
WaveNeuro One FSCV Workstation System Bundle, with NI Interface
[NEC-WN-ONE-P]
  1. Meunier, C.J.; McCarty, G.S.; Sombers, L.A. Tracking Carbon Microelectrode Impedance during Fast-Scan Cyclic Voltammetry. ACS Sens. 2025, 10, 3617-3627.
  2. Todorov, J.; McCarty, G.S.; Sombers, L.A. Mechanistic Insight into Tyrosine Oxidation at Carbon-Fiber Microelectrodes Revealed by Fast-Scan Cyclic Voltammetry. ACS Electrochemistry 2025.
  3. Qi, Y.; Jang, D.; Ryu, J.; Bai, T.; Shin, Y.; Gu, W.; Iyer, A.; Li, G.; Ma, H.; Liou, J.; van der Meer, M.; Qiang, Y.; Fang, H. Stabilized carbon coating on microelectrodes for scalable and interoperable neurotransmitter sensing. Nat. Commun. 2025, 16, 3300.
  4. Brooke, A.K.; Ojha, S.; Murrow, D.P.; Ross, A.E. Purinergic Receptor P2Y1 Modulates Catecholamine Signaling in Murine Mesenteric Lymph Nodes. ACS Chem. Neurosci. 2025, 16, 772-780.
  5. Peter, J.; Caldwell, K.C.; McClain, L.; Tchieu, J.; Ross, A.E.; Luo, Y. Inhibition of PTPRS function does not affect the survival or regeneration of dopaminergic neurons but alters synaptic function in the nigrostriatal pathway. Neurobiol. Dis. 2025, 213, 107023.
  6. Shrestha, K.; Chang, Y.; Zhang, Y.; Venton, B.J. Multiplexing FSCV and iGluSnFR3 Sensors Reveals Adenosine Transiently Inhibits Stimulated Dopamine and Glutamate Release. J. Neurochem. 2025, 169, e70147.
  7. Fernández-Vega, L.; Meléndez-Rodríguez, D.E.; Ospina-Alejandro, M.; Casanova, K.; Vázquez, Y.; Cunci, L. Development of a Neuropeptide Y-Sensitive Implantable Microelectrode for Continuous Measurements. ACS Sens. 2024.
  8. Sato, N.; Ohta, Y.; Haruta, M.; Takehara, H.; Tashiro, H.; Sasagawa, K.; Jongprateep, O.; Ohta, J. Electrochemical activities of Fe2O3-modified microelectrode for dopamine detection using fast-scan cyclic voltammetry. AIP Advances 2023, 13, 025026.
  9. Dumitrescu, E.; Copeland, J.M.; Venton, B.J. Parkin Knockdown Modulates Dopamine Release in the Central Complex, but Not the Mushroom Body Heel, of Aging Drosophila. ACS Chem. Neurosci. 2023, 14, 198-208.
  10. Keller, A.L.; Quarin, S.M.; Strobbia, P.; Ross, A.E. Platinum Nanoparticle Size and Density Impacts Purine Electrochemistry with Fast-Scan Cyclic Voltammetry. J. Electrochem. Soc. 2022, 169, 046514.
  11. Li, Y.; Jarosova, R.; Weese-Myers, M.E.; Ross, A.E. Graphene-Fiber Microelectrodes for Ultrasensitive Neurochemical Detection. Anal. Chem. 2022, 94, 4803-4812.
  12. Ostertag, B.J.; Cryan, M.T.; Serrano, J.M.; Liu, G.; Ross, A.E. Porous Carbon Nanofiber-Modified Carbon Fiber Microelectrodes for Dopamine Detection. ACS Appl. Nano Mater. 2022, 5, 2241-2249.
  13. Chang, Y.; Venton, B.J. Dual-Channel Electrochemical Measurements Reveal Rapid Adenosine is Localized in Brain Slices. ACS Chem. Neurosci. 2022, 13, 477-485.
  14. Liu, F.A.; Ardabili, N.; Brown, I.; Rafi, H.; Cook, C.; Nikopoulou, R.; Lopez, A.; Zou, S.; Hartings, M.R.; Zestos, A.G. Modified Sawhorse Waveform for the Voltammetric Detection of Oxytocin. J. Electrochem. Soc. 2022, 169, 017512.
  15. Dunham, K.E.; Venton, B.J. SSRI antidepressants differentially modulate serotonin reuptake and release in Drosophila. J. Neurochem. 2022, 162, 404-416.
  16. Kang, S.; Park, J.; Jeong, Y.; Oh, Y.; Choi, J. Second-Derivative-Based Background Drift Removal for Tonic Dopamine Measurement in Fast-Scan Cyclic Voltammetry. Anal. Chem. 2022, 94, 11459-11463.
  17. Li, Y.; Weese, M.E.; Cryan, M.T.; Ross, A.E. Amine-functionalized carbon-fiber microelectrodes for enhanced ATP detection with fast-scan cyclic voltammetry. Analytical Methods 2021, 13, 2320-2330.
  18. Asrat, T.M.; Cho, W.; Liu, F.A.; Shapiro, S.M.; Bracht, J.R.; Zestos, A.G. Direct Detection of DNA and RNA on Carbon Fiber Microelectrodes Using Fast-Scan Cyclic Voltammetry. ACS Omega 2021, 6, 6571-6581.
  19. Ardabili, N.G. Carbon Fiber Microelectrodes as Amino Acide Sensors using Fast Scan Cyclic Voltammetry. Master's Thesis, American University, 2021.
  20. He, X. Different Morphological Gold Nanoparticle-Modified Carbon Fiber microelectrodes for Enhanced Neurochemical Detection. Master's Thesis, American University, 2021.
  21. Wonnenberg, P.; Cho, W.; Liu, F.; Asrat, T.; Zestos, A.G. Polymer Modified Carbon Fiber Microelectrodes for Precision Neurotransmitter Metabolite Measurements. J. Electrochem. Soc. 2020, 167, 167507.
  22. Cho, W.; Liu, F.; Hendrix, A.; McCray, B.; Asrat, T.; Connaughton, V.; Zestos, A.G. Timed Electrodeposition of PEDOT:Nafion onto Carbon Fiber-Microelectrodes Enhances Dopamine Detection in Zebrafish Retina. J. Electrochem. Soc. 2020, 167, 115501.
  23. Regan, S.L.; Cryan, M.T.; Williams, M.T.; Vorhees, C.V.; Ross, A.E. Enhanced Transient Striatal Dopamine Release and Reuptake in Lphn3 Knockout Rats. ACS Chem. Neurosci. 2020, 11, 1171-1177.
  24. Walters, S.H.; Levitan, E.S. Vesicular Antipsychotic Drug Release Evokes an Extra Phase of Dopamine Transmission. Schizophr. Bull. 2020, 46, 643-649.
  25. Walters, S.H.; Shu, Z.; Michael, A.C.; Levitan, E.S. Regional Variation in Striatal Dopamine Spillover and Release Plasticity. ACS Chem. Neurosci. 2020, 11, 888-899.
  26. Delong, L.M.; Li, Y.; Lim, G.N.; Wairegi, S.G.; Ross, A.E. A microfluidic electrochemical flow cell capable of rapid on-chip dilution for fast-scan cyclic voltammetry electrode calibration. Anal. Bioanal. Chem. 2020, 412, 6287-6294.
  27. Shin, M.; Friedman, D.A.; Gordon, D.M.; Venton, B.J. Measurement of natural variation of neurotransmitter tissue content in red harvester ant brains among different colonies. Anal. Bioanal. Chem. 2020, 412, 6167-6175.
  28. Borgus, J.R.; Puthongkham, P.; Venton, B.J. Complex sex and estrous cycle differences in spontaneous transient adenosine. J. Neurochem. 2020, 153, 216-229.
  29. Mendoza, A.; Asrat, T.; Liu, F.; Wonnenberg, P.; Zestos, A.G. Carbon Nanotube Yarn Microelectrodes Promote High Temporal Measurements of Serotonin Using Fast Scan Cyclic Voltammetry. Sensors 2020, 20, 1173.
  30. Meunier, C.J.; McCarty, G.S.; Sombers, L.A. Drift Subtraction for Fast-Scan Cyclic Voltammetry Using Double-Waveform Partial-Least-Squares Regression. Anal. Chem. 2019, 91, 7319-7327.
  31. Calhoun, S.E.; Meunier, C.J.; Lee, C.A.; McCarty, G.S.; Sombers, L.A. Characterization of a Multiple-Scan-Rate Voltammetric Waveform for Real-Time Detection of Met-Enkephalin. ACS Chem. Neurosci. 2019, 10, 2022-2032.
  32. Lim, G.N.; Ross, A.E. Purine Functional Group Type and Placement Modulate the Interaction with Carbon-Fiber Microelectrodes. ACS Sens. 2019, 4, 479-487.
  33. Cryan, M.T.; Ross, A.E. Subsecond detection of guanosine using fast-scan cyclic voltammetry. The Analyst 2019, 144, 249-257.
  34. Nimbalkar, S.; Castagnola, E.; Balasubramani, A.; Scarpellini, A.; Samejima, S.; Khorasani, A.; Boissenin, A.; Thongpang, S.; Moritz, C.; Kassegne, S. Ultra-Capacitive Carbon Neural Probe Allows Simultaneous Long-Term Electrical Stimulations and High-Resolution Neurotransmitter Detection. Sci. Rep. 2018, 8, 6958.
  35. Smith, S.K.; Gosrani, S.P.; Lee, C.A.; McCarty, G.S.; Sombers, L.A. Carbon-Fiber Microbiosensor for Monitoring Rapid Lactate Fluctuations in Brain Tissue Using Fast-Scan Cyclic Voltammetry. Anal. Chem. 2018, 90, 12994-12999.
  36. Hensley, A.L.; Colley, A.R.; Ross, A.E. Real-Time Detection of Melatonin Using Fast-Scan Cyclic Voltammetry. Anal. Chem. 2018, 90, 8642–8650.
  37. Pyakurel, P.; Shin, M.; Venton, B.J. Nicotinic acetylcholine receptor (nAChR) mediated dopamine release in larval Drosophila melanogaster. Neurochem. Int. 2018, 114, 33–41.
  38. Lee, S.; Venton, B. Regional Variations of Spontaneous, Transient Adenosine Release in Brain Slices. ACS Chem. Neurosci. 2018, 9, 505–513.
  39. Shin, M.; Copeland, J.M.; Venton, B.J. Drosophila as a Model System for Neurotransmitter Measurements. ACS Chem. Neurosci. 2018, 9, 1872-1883.
  40. Wilson, L.R.; Panda, S.; Schmidt, A.C.; Sombers, L.A. Selective and Mechanically Robust Sensors for Electrochemical Measurements of Real-Time Hydrogen Peroxide Dynamics in Vivo. Anal. Chem. 2018, 90, 888-895.
  41. Wilson, L.R. Studying Oxidative Stress: Real-Time Detection of Hydrogen Peroxide and Dopamine in the Brain. Ph.D. Dissertation, North Carolina State University, 2018.
  42. Smith, S.K. Advancing Microbiosensor Development for Real-Time Electrochemical Detection of Multiple Analytes in Rat Brain Tissue. Ph.D. Dissertation, North Carolina State University, 2018.
  43. Mauterer, M...; Estave, P.M.; Holleran, K.M.; Jones, S.R. Measurement of Dopamine Using Fast Scan Cyclic Voltammetry in Rodent Brain Slices. Bio-Protocol 2018, 8, e2473.
  44. Hirabayashi, M. Glassy Carbon Neural Probes for Cortical and Spinal Electrochemical and Electrophysiological Sensing and Stimulation. Ph.D. Dissertation, University of California - San Diego, 2018.
  45. Castagnola, E.; Winchester Vahidi, N.; Nimbalkar, S.; Rudraraju, S.; Thielk, M.; Zucchini, E.; Cea, C.; Carli, S.; Gentner, T.Q.; Ricci, D.; Fadiga, L.; Kassegne, S. In Vivo Dopamine Detection and Single Unit Recordings Using Intracortical Glassy Carbon Microelectrode Arrays. MRS Advances 2018, 3, 1629–1634.
  46. Lee, K.H.; Lujan, J.L.; Trevathan, J.K.; Ross, E.K.; Bartoletta, J.J.; Park, H.O.; Paek, S.B.; Nicolai, E.N.; Lee, J.H.; Min, H.; Kimble, C.J.; Blaha, C.D.; Bennet, K.E. WINCS Harmoni: Closed-loop dynamic neurochemical control of therapeutic interventions. Sci. Rep. 2017, 7, 46675.
  47. Bucher, E.S.; Brooks, K.; Verber, M.D.; Keithley, R.B.; Owesson-White, C.; Carroll, S.; Takmakov, P.; McKinney, C.J.; Wightman, R.M. Flexible Software Platform for Fast-Scan Cyclic Voltammetry Data Acquisition and Analysis. Anal. Chem. 2013, 85, 10344-10353.
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Title
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DRU10120
WaveNeuro One FSCV System User Guide
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