Products

This Headstage Amplifier Cable kit is designed for use with the Pine Research WaveNeuro Fast-Scan Cyclic Voltammetry Potentiostat System.  The kit includes the DB-25 headstage cable with CP-305 bipolar stimulation connector, overall 24" long, five replaceable 1.5" microelectrode-headstage couplers, and 200 nA/V (5 MΩ), working driven headstage amplifier.  The modular design of the Pine Research headstage kits allows researchers to diagnose cable issues in a piecewise manner.  Say goodbye to that box of headstages that "just are not quite functioning correctly."

The headstage kit includes the cable, microelectrode-to-headstage couplers, and headstage amplifier.  Cables are available in 24" and 36" and couplers in 1.5" and 2.5".  The most common configurations are presented below, but additional lengths are available separately.

# Description Price in USD
For use with Pine Research WaveNeuro and UNC UEI Systems
[NEC-HS1]

kit includes UEI-compatible potentiostat to headstage cable with stimulation connector, overall 24" long, five replaceable 1.5" microelectrode-headstage couplers, and 200 nA/V (5 MΩ) working driven headstage amplifier

Headstage Kit includes the items listed below
RRHC0124-T

36" long, WaveNeuro and UEI Potentiostat compatible, includes CP-305 stimulator connector

AC01HS1

5 MΩ; 200 nA/V, working electrode driven

NOTE: A working electrode driven systems means the waveform is applied to the working electrode, which is then later software subtracted. Such a design is consistent with the general FSCV research community.

AC01HC0315-5

white reference, yellow working, pack of 5

Pine Research currently offers working driven headstage amplifiers.  In a working driven system, the reference electrode is grounded.  The FSCV potential waveform (ramp) is connected to the non-inverting input of the operational amplifier, while the working electrode is connected to the inverting input.  In this arrangement, the voltage at the microelectrode will follow the ramp applied to the inverting input.1

Even when no electrodes are connected (connector just in air) to the headstage amplifier cable, which is connected to the WaveNeuro, HDCV will show a current response that follows the applied waveform.  As described below, this is expected.

In this two-electrode configuration, current arising from electron-transfer reactions, such as the oxidation of dopamine, passes between reference and working electrodes.  The measured current passes through the headstage amplifer, where it is converted to voltage, and sums with the the ramp voltage at the inverting input. Mathematically,

$V_O=-(i_{in}\times R_F)+V_R$

where $V_O$ is the output voltage, $i_{in}$ is input current, $R_F$ is feedback resistor (gain), and $V_R$ is the CV ramp voltage.  By rearrangement, the signal voltage (proportional to the current across the $5\: M\Omega$ feedback resistor in the $200\:nA/V$ headstage) is then

$(V_R-V_O)=i_{in}\times R_F=V_{signal}$

HDCV software, which supports the WaveNeuro FSCV Potentiostat system, performs software subtraction of the ramp according to this relationship, resulting in only the true differential current measurement.1

(1) Takmakov, P.; McKinney, C. J.; Carelli, R. M.; Wightman, R. M. Instrumentation for Fast-Scan Cyclic Voltammetry Combined with Electrophysiology for Behavioral Experiments in Freely Moving Animals. Rev. Sci. Instrum. 2011, 82, 74302.

R.M. Wightman et. al. have reported on this topic in depth   If, after reviewing this document, you have any questions about our neuroelectrochemical research products, please do not hesitate to contact us.

All specifications are subject to change without notice.
Document # Title

DRU10120

WaveNeuro Fast Scan Cylic Voltammetry Potentiostat System User Guide

Contact us with any questions or support requests by phone or e-mail.

Our knowledgebase is the central repository for written content, including help topics, theory, application notes, specifications, and software information.

Software

Detailed information about our Software, which includes AfterMath and retired PineChem.

Applications

Application notes discuss practical aspects of conducting specific experiments.

Theory

Fundamental electrochemical theory presented in a brief and targeted manner.

Product Specifications

Review complete product specifications and compare products within a category here.